Dynamic Portfolio Strategy: Rebalancing Using Divestitures with Jerome Combes-Knoke

Strategy

Divestiture

· EPISODE

312

Dynamic Portfolio Strategy: Rebalancing Using Divestitures

Strategic focus is a prerequisite to strong corporate performance. Yet, without proactive efforts to maintain focus, companies can “drift” and become weighed down by misaligned business units. In this episode of the M&A Science Podcast, Jerome Combes-Knoke, Senior Vice President of Strategy and Corporate Development at Dotmatics (a portfolio company of Insight Partners), shares his broad M&A experience and presents his approach to portfolio strategy and rebalancing through divestitures.

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Jerome Combes-Knoke, Senior Vice President of Strategy and Corporate Development at Dotmatics (Insight Partners)

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Strategic focus is a prerequisite to strong corporate performance. Yet, without proactive efforts to maintain focus, companies can “drift” and become weighed down by misaligned business units.

‍

In this episode of the M&A Science Podcast, Jerome Combes-Knoke, Senior Vice President of Strategy and Corporate Development at Dotmatics (a portfolio company of Insight Partners), shares his broad M&A experience and presents his approach to portfolio strategy and rebalancing through divestitures.

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Things you will learn in this episode:

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Strategic focus in acquisitions, using Dotmatics’ approach.
Portfolio rebalancing and its challenges
Evaluating divestiture candidates
Building internal alignment for divestitures
Best practices to managing key risks

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Jerome Combes-Knoke

Jerome Combes-Knoke is a seasoned Corporate Development leader specializing in M&A, with a robust background in Strategy, Finance, and Cross-Functional Management. He has executed high-profile transactions, including PerkinElmer's $5.25 billion acquisition of BioLegend and the $5.3 billion GSK/Novartis asset swap. With experience across life sciences, financial services, and industrial technology, Jerome combines quantitative analysis, strategic insight, and social acumen to drive successful deals. Currently, at Dotmatics, he is focused on building a category leader in life science software research, supported by Insight Partners.

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